VCAM1 anticorps

N° du produit ABIN3025723

Cet anticorps anti-VCAM1 est un anticorps Souris Monoclonal détectant VCAM1 dans FACS, IF et BP. Adapté pour Humain.

Aperçu rapide pour VCAM1 anticorps (ABIN3025723)

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VCAM1 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Peptide (BP)

Clone: B-K9

Détail du produit anti-VCAM1 anticorps

Purification: Protein G affinity chromatography

Immunogène: Activated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM1 antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal dilution of the VCAM1 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL, Functional blocking: order BSA/azide free format

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the VCAM1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur VCAM1

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Autre désignation: VCAM1

Sujet: Recognizes a protein of 110  kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. L1CAM serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This mAb inhibits the binding of leukocytes to L1CAM on stimulated endothelial cells.

Pathways: Carbohydrate Homeostasis